Current board member and advisor for several biotech companies, Gilles Avenard is Medical Doctor and was the co-founder and COO of BioAlliance Pharma SA – ONXEO (NYSE EURONEXT) until 2010. He was notably involved in the development of several innovative medicines through to their official registration on both European and North-American territories. Before that, he worked as Project Director for Hoechst Marion Roussel (Sanofi) and was Medical Director of Bio-Transfusion (LFB).
Maryna graduated from Medical University in 2010 and has more than 8 years of experience in clinical trials area. She worked in CROs as well as with Sponsors directly as Clinical Research Associate and she was involved in multiple trials from phase II to IV. She joined ACTICOR`s team in September 2022 as Medical Assistant. Maryna`s role is to support Medical directors and managers at ACTICOR.
Professor at University Paris-Saclay (school of Pharmacy), Philippe Billiald is former president of the strategic committee and now scientific consultant at Acticor Biotech. He is an expert in the field of therapeutic and diagnostic antibody engineering. Philippe has published many papers in peer-reviewed scientific journals, books and scientific magazines in his area of expertise. He is also inventor in several international patents and serves in the editorial board of international, peer-reviewed journals: Antibodies, PLoS Negl Trop Dis.
Sophie has over 20 years’ experience in start-ups and mid-size companies within the biotechnology areas. She has a strong expertise in oncology, immunology and virology. Sophie has managed innovative R&D projects from the proof-of-concept to early clinical development. In her previous positions, Sophie was Vice-President Research and Early Clinical Development at PEP-Therapy, responsible for the development of peptide drug candidates in oncology. She was nonclinical R&D Director at InnaVirVax, developing innovative immune-based treatments for infectious diseases. She was Head of translational programs in oncology at Gustave Roussy Cancer Center. During her carrier, Sophie held various positions, at INSERM, CEA, Centre d’Immunologie Pierre Fabre, Bioalliance Pharma (Onxeo) and Stallergenes. Sophie holds a PhD in immunology from Paris VII Denis Diderot university. She is (co-)author of about 20 scientific publications and co-inventor of 9 patents.
Sirine is a medical doctor specialized on vascular surgery and holds a diploma on statistical methodology. After a career on Military Hospital in Tunis, Sirine decided to switch into the medical research field by embracing the career of Medical writer and Medical strategic development officer in 2009. She moved to Roche Tunisia in 2012 where she held the position of Country Medical Director at Roche Tunisia. She has to develop company’s medical strategy, ensure execution of operational plans and setting up clinical trial activities from study selection to publication. Sirine joined B2G Life Sciences since 2016 Clinical development physician and Medical Writer and she was appointed as Medical Director in early 2021. She was responsible for setting up the clinical strategy and develop the company network. She joined Acticor in 2022 as Medical Research Manager.
Alexandra Brochand, PharmD, has a specialization in pharmaceutical biotechnologies and innovative therapies. She worked for 8 years in the French Blood Establishment as Qualified person for advanced therapy medicinal products. She has contributed to the development of the pharmaceutical activity and the associated quality system, including the risk management strategy to be implemented to secure the process and the manufactured products. She joined Acticor Biotech in 2023 as Quality manager and she is involved in the continuous improvement of the activities in collaboration with the different departments of the company.
Kenza CHAIEB is studying for a Master's degree in Health Engineering, in the field of Health Products Design and Production at the Faculty of Pharmacy of Montpellier. During her training, she had the opportunity to do internships in the field of clinical research. Passionate about the pharmaceutical industry and medical research, Kenza wishes to develop skills in the management of quality systems. She wishes to participate in the implementation of efficient and effective tools that allow to meet the regulatory requirements applicable to clinical research. Kenza joined the Acticor team as an apprentice in September 2022. Under the responsibility of the Quality Assurance Director, Kenza participates in the Glenzocimab development project and in the implementation of specific procedures for clinical projects.
CEO and Founder of Agile Capital Markets; Advisor of several biotech & medtech companies (among which EOS imaging, Cellnovo, PKvitality), Eric raised over 200M€ in public and private fund raising. He was previously CFO of Mauna Kea Technologies (Euronext®: MKEA), Hybrigenics (Euronext®: ALHYG) and Teva Pharmaceuticals France (NASDAQ®: TLV). He led 2 IPO on Euronext® raising 62M€. He was also Head of Hybrigenics Business Services and Head of Operations (R&D and Production) at Mauna Kea Technologies.
Andrea Comenducci, MD, Medical Director at Acticor Biotech. Educated as a General Practitioner, Andrea has more than 25-year experience in the pharmaceutical industry. He assumed various functions from International Project leader and Senior Medical Advisor to Medical Director in medium and large companies. His preferred therapeutic area is the cardiovascular field in which he has vast experience in coronary artery diseases, high blood pressure, heart failure, atherosclerosis acquired in large worldwide clinical trials such as the GUSTO V-TIMI 14 study, STABILITY and SOLID-TIMI 52 studies. In November 2018, Andrea joined Acticor Biotech with the role of Medical Director in order to take up new exciting challenges in acute ischemic stroke, Covid-19 pandemic and pulmonary embolism.
Master’s degree in Bioengineering : Biotechnologies applied to health, Marion Galaup has over 10 years’ experience in the biotechnology areas (Novartis, InnaVirVax and DBV Technologies. She joined Acticor Biotech in 2022 as an analytical project manager.
Shahin Gharakhanian MD, DPH, based in Boston MA, is an Executive Medical Consultant for Acticor-Biotech since 2019 and Heads Clinical/Medical Operations in the United States for the company. Dr Gharakhanian is a Physician-Executive with expertise in Pharmaceutical Medicine, Leadership and Management, and an international track record:(1) [Clinical Medicine] Clinical Practice @ AP-HP [Assistance Publique–Hopitâux de Paris, Paris Public Academic Hospitals] the largest hospital system in Europe and one of the largest globally. (2) [Pharmaceutical Medicine] Broad experience including Vice-President of Vertex Pharmaceuticals Inc., Global R&D and Corporate Operating Council Member in Cambridge MA, USA. He has clinically developed/launched four novel treatments including a “Blockbuster”. (3) [Executive Medical Consultant] Shahin Gharakhanian MD Consulting LLC, is a consultancy practice based @ CIC: Cambridge Innovation Center, which to date, has provided expertise to 20 companies. Dr Gharakhanian’s medical education has been at Paris-Sorbonne University and Harvard University Medical School.
Bérengère Hennebelle, Pharm.D, has 20 years of experience in the pharmaceutical industry. She began her career in pharmaceutical development services in medium-sized companies (Guerbet, HRA Pharma), combining CMC development and technical-regulatory activities on an international scale. After a university degree in biological therapies, she turned to biotechnological products. She contributed to the CMC strategy and coordinated CMC dossiers of biologics in the FDA and EMA registration phase for a recombinant protein at LFB and then for a gene therapy product at Gensight Biologics. She joined Acticor in 2022 to take over CMC regulatory activities.
With a Master’s degree in Accounting and Finance, Aymeric was an Audit Manager at Grant Thornton for 7 years. He worked on listed and non-listed companies and specialized in the Biotech industry.
After a Master degree in pharmaceutical biotechnology and innovative therapy, Jessica (PharmD) joined Acticor Team in November 2019 as Regulatory and Clinical Associate after completing her end of study internship in Regulatory Affairs and CMC departments. She’s now Regulatory Affairs Manager and monitors clinical projects’ regulatory activities.
Martine Jandrot-Perrus obtained her medical degree in 1977 (University Paris 5) and turned towards medical research. After completing her training in Biochemistry/Enzymology (University Paris Sud), she joined INSERM (the French National Institute on Health and Medical Research) in 1982. She was at the head of the team Molecular and Cellular Mechanisms of Thrombosis from 2003 to 2013. She is now Emeritus Research Director at the Laboratory for Vascular Translational Science (INSERM/University of Paris, Bichat hospital). Her work on haemostasis and thrombosis, and her expertise on platelets and in particular on glycoprotein VI are internationally recognized. Her most notable contributions in this field include the cloning of GPVI, the first description of a subject with a congenital deficit, the identification of new ligands of GPVI and the characterization of its role in the formation of thromboses. She obtained and characterized the antithrombotic properties of the anti-GPVI monoclonal antibody 9O12, precursor of glenzocimab. Author of 11 patents and 171 publications in international journals (h index 40) she received several awards from the Bettencourt-Schueller Foundation (Coup d’Elan 2002), SGAM-ASSET Foundation (Therapeutic Innovation 2007), French Academy of Sciences (2007) and the Esteemed Career Award from the International Society on Thrombosis and Haemostasis in 2019. Since the foundation of Acticor Biotech, she is actively involved in its development as scientific expert.
Laurie Jullien, PharmD. with a Master in International Drug Development and Registration is directing the regulatory affairs. She has more than 9 years of international experience, starting her career at Genentech (USA) and then at Roche (UK). She joined Acticor Biotech in 2016 to built the Regulatory Affairs and Quality Department, ensuring the regulatory activities from the non clinical development to the first-in-human and first-in-patient studies, and the development of the quality policy of the company. From November 2020, she is taking the role of Head of Regulatory Affairs full time, working on the global regulatory strategy, interactions with health authorities and the management of the regulatory department.
Marilyn has over 20 years’ experience in pharmaceutical development and global clinical project management especially in oncology, virology and Intensive care unit. She previously assumed the functions of International Clinical Project Manager in pharmaceutical companies and CRO (Clinical Research Organization). Before that, she spent the beginning of her career in marketing and participated in the launching of several innovative products in oncology for Chiron and Aventis.
Philippe Le Berre, MD, MSc., Consultant Medical Director at Acticor Biotech Clinical Development. Philippe is board certified in Vascular Medicine and Clinical Pharmacology. He benefits from an in-depth expertise in leading early and regulatory Medical Development projects, Translational Medicine and as Senior Medical Advisor mainly acquired within IPSEN, Pierre Fabre Laboratories and as independent expert. He has a large experience in all cardiology and vascular diseases, athero-thrombosis and CNS acquired in international clinical trials and worldwide clinical research collaborations. In parallel he always remained vascular practitioner closed to patients as Hospital Resident and within Private medical centers. Philippe Le Berre, MD, MSc, Directeur médical consultant chez Acticor Biotech Clinical Development.
Following an STMG baccalaureate, Antoine turned to the world of communication. He is preparing a BTS in communication within Acticor Biotech. He joined the company as a communication and IT assistant in September 2020.
Kristell Lebozec holds a master's degree in biotechnology engineering and a PhD in pharmacological sciences. She has worked in university laboratories (Institut Gustave Roussy and Centre de Recherche des Cordeliers) and in industry (DNA Therapeutics and I-Stem). She joined the company in 2015 and was responsible for the early-stage development of glenzocimab. Between 2019 and 2021, she was responsible for the pharmaceutical and non- clinical development of glenzocimab. Since 2022, her activities focus on the pharmaceutical development of glenzocimab (cell banks, drug substance, drug product and analytical methods) on a full-time basis. She is responsible for the management of the department, the outsourcing of activities to CDMO/CROs and the regulatory pharmaceutical strategy. Kristell holds a master’s degree in biotechnology engineering and a PhD in Pharmacological Sciences from Paris Saclay University. She has published 7 papers, 3 of which as first author.
PharmD specialized in Pharmacotechny-Biopharmacy, Christelle Lesieur shows a 4.5 years-experience in the pharmaceutical industry. After a role of Formulation Scientist at Sanofi in biologics development, Christelle has been working as CMC Project Manager at IDD, before joining Acticor Biotech in 2022 at the position of Pharmaceutical Development Project Manager. In charge of the drug substance and the drug product manufacturing, she is responsible for the whole manufacturing process of ACT017.
Dedicated Clinical Trial Assistant (CTA) with different project experiences within CRO (I3 Life Science, Hays Pharma, Kelly Outsourcing Consultant Group) and Pharmaceutical Industries (Pfizer, Roche, Chiesi and Lilly) from Project Launching to Close-Out (through different processes of Site Start-Up, TMF, e-TMF Archiving, Budget Management, Study follow-up, etc and Close-out).
Sandra has more than 20 years of administrative and commercial management experience in various jobs in the pharmaceutical industry, first with Alergovet on the national market and then with Stallergenes on the international market. This signifiant experience allows her today to offer her services as an independent office manager to small and medium-sized companies and startups. She has worked with Acticor Biotech since October 2022 on office manager and cross-functional project management missions
Adeline Meilhoc, DPsy, is directing the global clinical trials in bringing her expertise to ACTICOR Biotech in team management and strategic & operational study structuration. She has spent her career in the clinical Drug Development in pharma and contract research organization entities, both as VP Medical Affairs & Clinical Operations and as VP Business Development. She has built several departments in the medical and clinical trial feasibility, in study start-up and in medical imaging as well as commercial and marketing development. Specializing in building business relationships, she has spent the last few years developing Marketing & Sales strategies for various eClinical tools to Healthcare Professionals and Medical Device companies, in addition to her own businesses. Her strong expertise in Real World Evidence and in the operational aspect of market access has broaden her vision of drug development and launch. She is clinical psychologist - ICP - EPP of Paris, specialized in the field of Health & Society.
Stéphanie PAUL, Clinical Operations Trainer, at Acticor Biotech, background of study research nurse. She has more than 15 years of experience in a clinical research center in CHRU from Brest. She assumed various functions from study coordinator in different therapeutic domains: respiratory, thromboembolic diseases, vascularitis and neurological area. She supervised both French and international trials, and realized all the technical care, in respect of GCP. She comes from hospital so she could be a veritable resource for the training staff.
Dr Plétan is an expert in clinical development within the pharmaceutical industry. He previously held leadership positions at Roche, Pfizer, Sanofi and Pierre Fabre. Before joining Acticor Biotech, Dr Plétan served as head of the Medical Division and was a board member of the Foundation at Roche France and member of the Global Medical Affairs Committee at Hoffman La Roche Ltd (Switzerland). Prior to these activities, he was also vice-president, head of Medical and Scientific Division and board member of the Foundation at Pfizer.
Anitha Pobbati an accomplished healthcare professional , pursued Msc in Global business management from Rennes school of Business and Bsc in Advanced Nursing. She is skilled in management of clinical studies and Business acumen. Added experience in Marketing, communications and Management. She possess meticulous clinical management adept and the development & implementation of clinical practices. She is passionate to work and develop the Health services to provide better health systems for the wellness of patients. She joined Acticor Biotech in 2022 as Clinical Operations Trainer.
PharmD. – Master in Quality Assurance – Pharmaceutical Products. Victoria Rutman has 6 years of hands-on experience in the pharmaceutical industry. Before joining Acticor Biotech, she served as Quality Pharmacist at Innothera and at Orphan Europe. She joined Acticor in 2019 and was promoted Head of Quality at the end of 2020. She works in close collaboration with all departments to monitor regulatory compliance, continuous improvement and also on the quality policy of the company.
Anouar has more than 20 years of experience working in the pharmaceutical industry. He began his career at Gustave Roussy Institute, then ICON Clinical research and Nanobiotix, holding various positions and acting as “Global Clinical Project Manager” and “Associate Director Clinical Operations” afterwards.
Since 2015, Veronia was involved in numerous clinical trials from phase I to phase IV, mainly in oncology (solid tumors and lymphoma as well) as CRA and then as Lead CRA. I work for numerous of CRO such as Altizem, Aepodia, DOCS/ICON or Labcorp.
Elie has 10 years of experience in major companies and public-private bodies within the biotechnology area. Committed to bring breakthrough innovations to patient as fast as possible, he has a broad expertise in several therapeutic areas. Elie has managed strategic alliances of innovative R&D projects from the proof-of-concept to clinical development. During his carrier, he held various positions, at Curie Institute, Total New energy, Roche, and Conectus. Elie holds a Master in Molecular and Cellular Biology from Ecole Normale Supérieure de Lyon, and a PhD in Molecular Biology done within Pasteur Institute (Paris). He joined Acticor Biotech in 2021 as Head of Global Project Coordination.
Chloé obtained a PharmD from the University of Paris Descartes and a master’s degree in Clinical Operations Management from the Montpellier University. During her studies, she worked as a clinical project manager in oncology and neuroscience at Roche Thailand and Roche France. She is passionate about several areas of medical and public health research to address unmet medical needs and understand how the driving forces of science and technology can interact to improve the patient experience.